Calcium intreactions

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Calcium

Calcium and Medication Interactions

Calcium supplements have the potential to interact with several prescription and over the counter medications. Further information about these interactions is described below. Some examples of medications that may interact with calcium include:

digoxin
fluroquinolones
levothyroxine
antibiotics in tetracycline family
tiludronate disodium
anticonvulsants such as phenytoin
thiazide, type of diuretic
glucocorticoids
mineral oil or stimulant laxatives
aluminum or magnesium containing antacids
Calcium supplements may decrease levels of the drug digoxin, a medication given to heart patients [101]. The interaction between calcium and vitamin D supplements and digoxin may also increase the risk of hypercalcemia. Calcium supplements also interact with fluoroquinolones (a class of antibiotics including ciprofloxacin), levothyroxine (thyroid hormone) used to treat thyroid deficiency, antibiotics in the tetracycline family, tiludronate disodium (a drug used to treat Paget's disease), and phenytoin (an anti-convulsant drug). In all of these cases, calcium supplements decrease the absorption of these drugs when the two are taken at the same time [101,102].

Thiazide, and diuretics similar to thiazide, can interact with calcium carbonate and vitamin D supplements to increase the chances of developing hypercalcemia and hypercalciuria (elevated levels of calcium in urine) [102]. Aluminum and magnesium antacids can both increase urinary calcium excretion. Mineral oil and stimulant laxatives can both decrease dietary calcium absorption. Furthermore, glucocorticoids (for example: prednisone) can cause calcium depletion and eventually osteoporosis, when used for more than a few weeks [102].

Calcium:What is it?

What is the recommended intake for calcium?

What foods provide calcium?

Helping hints for meeting your calcium needs

What affects calcium absorption and excretion?

Calcium's role in health and disease prevention

When can a calcium deficiency occur?

Who may need extra calcium?

Is there a health risk of too much calcium?

Supplemental sources of calcium