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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Allergy What are the controversial diagnostic techniques?
One controversial diagnostic technique is cytotoxicity testing, in which a food allergen is added to a patient's blood sample. A technician then examines the sample under the microscope to see if white cells in the blood "die." Scientists have evaluated this technique in several studies and have not been found it to effectively diagnose food allergy.
Another controversial approach is called sublingual or, if it is injected under the skin, subcutaneous provocative challenge. In this procedure, dilute food allergen is administered under the tongue of the person who may feel that his or her arthritis, for instance, is due to foods. The technician then asks the patient if the food allergen has aggravated the arthritis symptoms. In clinical studies, researchers have not shown that this procedure can effectively diagnose food allergies.
An immune complex assay is sometimes done on patients suspected of having food allergies to see if there are complexes of certain antibodies bound to the food allergen in the bloodstream. It is said that these immune complexes correlate with food allergies. But the formation of such immune complexes is a normal offshoot of food digestion, and everyone, if tested with a sensitive enough measurement, has them. To date, no one has conclusively shown that this test correlates with allergies to foods.
Another test is the IgG subclass assay, which looks specifically for certain kinds of IgG antibody. Again, there is no evidence that this diagnoses food allergy.
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Difference between Food Allergy and Intolerances How Allergic Reactions Work? What are the Common Food Allergies? What is Cross Reactivity?
What are the Differential Diagnoses? How is allergy Diagnosed?
What is Exercise-Induced Food Allergy? What are the Treatments available? How does allergy affect Infants and Children? What are the Controversial Issues? What are the Controversial Treatments? |
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